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1

Noncovalent Synthesis: Using Physical-Organic Chemistry To Make Aggregates

Whitesides, George M., Simanek, Eric E., Mathias, John P., Seto, Christopher T., Chin, Donovan, Mammen, Mathai, Gordon, Dana M.

Journal:

Accounts of Chemical Research

Année:

1995

Langue:

english

Fichier:

PDF, 1.81 MB

english, 1995

2

Polyvalente Wechselwirkungen in biologischen Systemen: Auswirkungen auf das Design und die Verwendung multivalenter Liganden und Inhibitoren

Mathai Mammen, Seok-Ki Choi, George M. Whitesides

Journal:

Angewandte Chemie

Année:

1998

Langue:

german

Fichier:

PDF, 1001 KB

german, 1998

3

Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

Mathai Mammen, Seok-Ki Choi, George M. Whitesides

Journal:

Angewandte Chemie International Edition

Année:

1998

Langue:

english

Fichier:

PDF, 998 KB

english, 1998

4

ChemInform Abstract: Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors

Mathai Mammen, Seok-Ki Choi, George M. Whitesides

Journal:

Année:

1999

Fichier:

PDF, 25 KB

1999

5

Design and synthesis of hydrogen-bonded aggregates. Theory and computation applied to three systems based on the cyanuric acid-melamine lattice

Eric E Simanek, Mathai Mammen, Dana M Gordon, Donovan Chin, John P Mathias, Christopher T Seto, George M Whitesides

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 612 KB

english, 1995

6

Discovery of muscarinic acetylcholine receptor antagonist and beta 2 adrenoceptor agonist (MABA) dual pharmacology molecules

Adam D. Hughes, Kay H. Chin, Sarah L. Dunham, Jeffrey R. Jasper, Kristin E. King, Tae Weon Lee, Mathai Mammen, Jerri Martin, Tod Steinfeld

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 469 KB

english, 2011

7

Optically controlled collisions of biological objects to evaluate potent polyvalent inhibitors of virus-cell adhesion

Mathai Mammen, Kristian Helmerson, Rani Kishore, Seok-Ki Choi, William D. Phillips, George M. Whitesides

Journal:

Chemistry & Biology

Année:

1996

Langue:

english

Fichier:

PDF, 1.87 MB

english, 1996

8

Monomeric inhibitors of influenza neuraminidase enhance the hemagglutination inhibition activities of polyacrylamides presenting multiple C-sialoside groups

Seok-Ki Choi, Mathai Mammen, George M. Whitesides

Journal:

Chemistry & Biology

Année:

1996

Langue:

english

Fichier:

PDF, 1.70 MB

english, 1996

9

Detection of hydrogen-bonded supramolecular complexes using electrospray ionization from chloroform

Xueheng Cheng, Quanyin Gao, Richard D. Smith, Eric E. Simanek, Mathai Mammen, George M. Whitesides

Journal:

Rapid Communications in Mass Spectrometry

Année:

1995

Langue:

english

Fichier:

PDF, 424 KB

english, 1995

10

Phenylketonuria in Indian children

Gertrude E. Joshua, S. Chandy, A. N. Radhakrishnan, D. Mammen, K. V. Mathai

Journal:

Journal of Inherited Metabolic Disease

Année:

1978

Langue:

english

Fichier:

PDF, 982 KB

english, 1978

11

Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation

Lambertus P. W. Witte, Noach de Haas, Mathai Mammen, Eric L. Stangeland, Tod Steinfeld, Jayashree Aiyar, Martin C. Michel

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 302 KB

english, 2011

12

Porokeratosis of Mibelli with a Dentigerous Cyst

Rachel Mathai, Mary Jacob, K. E. Mammen, Doss Sudarshanam

Journal:

International Journal of Dermatology

Année:

1990

Langue:

english

Fichier:

PDF, 4.07 MB

english, 1990

13

Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β2-adrenoceptor agonist (MABA)

Alexander McNamara, Tod Steinfeld, Maria Teresa Pulido-Rios, Eric Stangeland, Sharath S. Hegde, Mathai Mammen, William J. Martin

Journal:

Pulmonary Pharmacology & Therapeutics

Année:

2012

Langue:

english

Fichier:

PDF, 563 KB

english, 2012

14

Generation and in Situ Evaluation of Libraries of Poly(acrylic acid) Presenting Sialosides as Side Chains as Polyvalent Inhibitors of Influenza-Mediated Hemagglutination

Choi, Seok-Ki, Mammen, Mathai, Whitesides, George M.

Journal:

Journal of the American Chemical Society

Année:

1997

Langue:

english

Fichier:

PDF, 427 KB

english, 1997

15

Estimating the Entropic Cost of Self-Assembly of Multiparticle Hydrogen-Bonded Aggregates Based on the Cyanuric Acid·Melamine Lattice

Mammen, Mathai, Shakhnovich, Eugene I., Deutch, John M., Whitesides, George M.

Journal:

Journal of Organic Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 144 KB

english, 1998

16

Effective Inhibitors of Hemagglutination by Influenza Virus Synthesized from Polymers Having Active Ester Groups. Insight into Mechanism of Inhibition

Mammen, Mathai, Dahmann, Georg, Whitesides, George M.

Journal:

Journal of Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 1.46 MB

english, 1995

17

Pharmacy and Self-Report Adherence Measures to Predict Virological Outcomes for Patients on Free Antiretroviral Therapy in Tamil Nadu, India

McMahon, James H., Manoharan, Anand, Wanke, Christine A., Mammen, Shoba, Jose, Hepsibah, Malini, Thabeetha, Kadavanu, Tony, Jordan, Michael R., Elliott, Julian H., Lewin, Sharon R., Mathai, Dilip

Journal:

AIDS and Behavior

Année:

2013

Langue:

english

Fichier:

PDF, 193 KB

english, 2013

18

Determination of the Binding of Ligands Containing the N-2,4-dinitrophenyl Group to Bivalent Monoclonal Rat Anti-DNP Antibody Using Affinity Capillary Electrophoresis

Mammen, Mathai., Gomez, Frank A., Whitesides, George M.

Journal:

Analytical Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 994 KB

english, 1995

19

Predicting the Relative Stabilities of Multiparticle Hydrogen-Bonded Aggregates Based on the Number of Hydrogen Bonds and the Number of Particles and Measuring These Stabilities with Titrations Using Dimethyl Sulfoxide

Mammen, Mathai, Simanek, Eric E., Whitesides, George M.

Journal:

Journal of the American Chemical Society

Année:

1996

Langue:

english

Fichier:

PDF, 274 KB

english, 1996

20

Characterization of Hydrogen-Bonded Aggregates in Chloroform by Electrospray Ionization Mass Spectrometry

Cheng, Xueheng, Gao, Quanyin, Smith, Richard D., Simanek, Eric E., Mammen, Mathai, Whitesides, George M.

Journal:

Journal of Organic Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 61 KB

english, 1996

21

Representing Primary Electrophoretic Data in the 1/Time Domain: Comparison to Representations in the Time Domain

Mammen, Mathai, Colton, Ian J., Carbeck, Jeffrey D., Bradley, Ryan, Whitesides, George M.

Journal:

Analytical Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 387 KB

english, 1997

22

Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase

Cheng, Xueheng, Chen, Ruidan, Bruce, James E., Schwartz, Brenda L., Anderson, Gordon A., Hofstadler, Steven A., Gale, David C., Smith, Richard D., Gao, Jinming, Sigal, George B., Mammen, Mathai, White

Journal:

Journal of the American Chemical Society

Année:

1995

Langue:

english

Fichier:

PDF, 309 KB

english, 1995

23

Using a Convenient, Quantitative Model for Torsional Entropy To Establish Qualitative Trends for Molecular Processes That Restrict Conformational Freedom

Mammen, Mathai, Shakhnovich, Eugene I., Whitesides, George M.

Journal:

Journal of Organic Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 152 KB

english, 1998

24

Polyacrylamides Bearing Pendant α-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus: The Strong Inhibition Reflects Enhanced Binding through Cooperative Polyvalent Interactions

Sigal, George B., Mammen, Mathai, Dahmann, Georg, Whitesides, George M.

Journal:

Journal of the American Chemical Society

Année:

1996

Langue:

english

Fichier:

PDF, 507 KB

english, 1996

25

Treating Electrostatic Shielding at the Surface of Silica as Discrete Siloxide·Cation Interactions

Mammen, Mathai, Carbeck, Jeffrey D., Simanek, Eric E., Whitesides, George M.

Journal:

Journal of the American Chemical Society

Année:

1997

Langue:

english

Fichier:

PDF, 213 KB

english, 1997

26

Targets for intervention to improve virological outcomes for patients receiving free antiretroviral therapy in Tamil Nadu, India

McMahon, James H., Manoharan, Anand, Wanke, Christine, Mammen, Shoba, Jose, Hepsibah, Malini, Thabeetha, Kadavanu, Tony, Jordan, Michael R., Elliott, Julian H., Lewin, Sharon R., Mathai, Dilip

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 147 KB

english, 2014

27

Gastrointestinal Complications in Patients with Chronic Kidney Disease—A 5-Year Retrospective Study from a Tertiary Referral Center

Thomas, Renu, Panackal, Charles, John, Mammen, Joshi, Harshad, Mathai, Sunil, Kattickaran, Joseph, Iqbal, Mohammed

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 778 KB

english, 2013

28

Discovery of ( R )-1-(3-((2-Chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1′-Biphenyl]-2-ylcarbamate (TD-5959, GSK961081, Batefenterol): First-in-Class Dual Pharmacology Multivalent Muscarinic Antagonist and β 2 Agonist (MABA) for the Treatment of Chronic Obstructive Pulmonary Disease (COPD)

Hughes, Adam D., Chen, Yan, Hegde, Sharath S., Jasper, Jeffrey R., Jaw-Tsai, Sarah, Lee, Tae-Weon, McNamara, Alexander, Pulido-Rios, M. Teresa, Steinfeld, Tod, Mammen, Mathai

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.19 MB

english, 2015

29

SPIE Proceedings [SPIE BiOS '98 International Biomedical Optics Symposium - San Jose, CA (Tuesday 27 January 1998)] Optical Investigations of Cells In Vitro and In Vivo - Optically controlled collisions of biological objects

Davies, Benjamin J., Kishore, Rani, Mammen, Mathai, Helmerson, Kristian, Choi, Seok-Ki, Phillips, William D., Whitesides, George M., Farkas, Daniel L., Leif, Robert C., Tromberg, Bruce J.

Année:

1998

Langue:

english

Fichier:

PDF, 958 KB

english, 1998

30

Duration by Design: Discovery of Revefenacin, the First-in-Class Nebulized Once-Daily Bronchodilator for the Treatment of Patients With COPD

Ji, Yuhua, Husfeld, Craig, Pulido-Rios, M. Teresa, McNamara, Alexander, Obedencio, Glenmar P., Baldwin, Mike, Bourdet, David, Hegde, Sharath, Mammen, Mathai, Moran, Edmund

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 99 KB

english, 2016

31

Pharmacological properties of revefenacin (TD-4208), a novel, nebulized long-acting, and lung selective muscarinic antagonist, at human recombinant muscarinic receptors and in rat, guinea pig, and human isolated airway tissues

Hegde, Sharath S., Pulido-Rios, M. Teresa, Luttmann, Mark A., Foley, James J., Hunsberger, Gerald E., Steinfeld, Tod, Lee, TaeWeon, Ji, Yuhua, Mammen, Mathai M., Jasper, Jeffrey R.

Journal:

Pharmacology Research & Perspectives

Année:

2018

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2018